Sunitha Krishnan has dedicated her life to rescuing women and children from sex slavery, a multimilion-dollar global market. In this courageous talk, she tells three powerful stories, as well as her own, and calls for a more humane approach to helping these young victims rebuild their lives.

In this prophetic 2003 talk -- just days before Dolly the sheep was stuffed -- biotech ethicist Gregory Stock looked forward to new, more meaningful (and controversial) technologies, like customizable babies, whose adoption might drive human evolution.

In a breakthrough experiment, Aaron O'Connell has blurred that distinction by creating an object that is visible to the unaided eye, but provably in two places at the same time. In this talk he suggests an intriguing way of thinking about the result.

Henry Markram is director of Blue Brain, a supercomputing project that can model components of the mammalian brain to precise cellular detail -- and simulate their activity in 3D.

Josette Sheeran, the head of the UN's World Food Program, talks about why, in a world with enough food for everyone, people still go hungry, still die of starvation, still use food as a weapon of war. Her vision: "Food is one issue that cannot be solved person by person. We have to stand together."

Matt Ridley shows how, throughout history, the engine of human progress has been the meeting and mating of ideas to make new ideas. It's not important how clever individuals are, he says; what really matters is how smart the collective brain is.

Charles Leadbeater weaves a tight argument that innovation isn't just for professionals anymore. Passionate amateurs, using new tools, are creating products and paradigms that companies can't.